Flavonoids and Lignans fromVirola surinamensisTwigs and theirin vitroActivity againstTrypanosoma cruzi
- 1 October 1998
- journal article
- letter
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 64 (07) , 667-669
- https://doi.org/10.1055/s-2006-957548
Abstract
Dichloromethane extracts from twigs of Virola surinamensis (Myristicaceae) showed in vitro trypanosomicidal activity against trypomastigote form of Trypanosoma cruzi. The extract, fractionated by preparative circular chromatography and preparative high-performance liquid chromatography yielded two steroids, two lignans, five flavonoids, and one polyketide. Among the isolated compounds, the lignans presented the highest trypanosomicidal activity.Keywords
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