RAPID COMMUNICATION
- 1 January 1987
- journal article
- research article
- Published by Japan Endocrine Society in Endocrinologia Japonica
- Vol. 34 (2) , 319-323
- https://doi.org/10.1507/endocrj1954.34.319
Abstract
Morphological investigation of the endogenous digitalis-like substance (EDLS) characterized as a natriuretic humoral agent has not been carried out to date; but EDLS can be detected indirectly by immunohistochemistry using cross-reactivity with digoxin-antibody. In this report, the brain and other organs of the rat and macaque were immunostained using commercially supplied digoxin-specific antibodies. The immunoreactive substances were mainly observed in the neurons of hypothalamic paraventricular and supraoptic nuclei, and varicose fibers in some areas of the hypothalamus and infundibulum. No immunopositive substances were detected in the pituitary anterior lobe, adrenal gland, or kidney of the rat.This publication has 8 references indexed in Scilit:
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