Autoregulation of iclR, the gene encoding the repressor of the glyoxylate bypass operon
Open Access
- 1 January 1996
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 178 (1) , 321-324
- https://doi.org/10.1128/jb.178.1.321-324.1996
Abstract
The aceBAK operon was partially induced by a multicopy plasmid which carried the promoter region of the gene which encodes its repressor, iclR. Gel shift and DNase I analyses demonstrated that IclR binds to its own promoter. Disruption of iclR increased the expression of an iclR::lacZ operon fusion. Although aceBAK and iclR are both regulated by IclR, aceBAK expression responds to the carbon source, while expression of iclR does not.Keywords
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