Relationships between cytoskeletal proteins and the toxic effects of drugs.
- 1 January 1997
- journal article
- review article
- Published by Japanese Society of Toxicology in The Journal of Toxicological Sciences
- Vol. 22 (5) , 383-395
- https://doi.org/10.2131/jts.22.5_383
Abstract
Many cell functions and aspects of cell configuration are linked with changes in cytoskeletal proteins, by intracellular signal transduction. Histochemical and pathophysiological changes caused by toxins or drugs affect on dynamic aspects of cytoskeletal proteins. Here we review that biochemical and molecular biological properties of the microtubules and microfilaments and the relationships between these cytoskeletal proteins and the toxic effects of drugs and toxins. The intracellular signaling pathway makes use of cytoskeletal proteins.Keywords
This publication has 0 references indexed in Scilit: