MODIFICATION OF THE CHOLINE DEFICIENCY SYNDROME IN THE RAT BY SOMATOTROPHIN AND HYDROCORTISONE1
- 1 December 1953
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 53 (6) , 661-666
- https://doi.org/10.1210/endo-53-6-661
Abstract
Anterior pituitary growth hormone at a dosage of 2.5 mg./day augmented the renal damage caused by a choline deficient diet, but did not affect liver lipid accumulation. No greater effect was obtained by doubling the dosage. Growth hormone while stimulating body growth in animals on an adequate diet was ineffective in preventing the wt. loss occasioned by the deficient diet. Hydrocortisone prevented the typical renal lesions caused by choline deficiency, but did not restore a normal cytoarchitecture. It did not prevent the fatty liver observed in animals on the deficient diet.Keywords
This publication has 4 references indexed in Scilit:
- CONJOINT EFFECTS OF PYRIDOXINE DEFICIENCY AND ANTERIOR PITUITARY GROWTH HORMONE ADMINISTRATION IN THE RATEndocrinology, 1953
- Growth Effects of Desoxycorticosterone and Cortisone with Special Reference to Compensatory Renal HypertrophyExperimental Biology and Medicine, 1952
- Choline Requirement of Rats as Influenced by Age, Strain, Vitamin B12 and Folacin.Experimental Biology and Medicine, 1951
- Interrelationship of Vitamin B12 and Choline. I. Effect on Hemorrhagic Kidney Syndrome in the RatExperimental Biology and Medicine, 1949