SELECTIVE DEPLETION OF NORADRENALINE IN THE ADRENALS OF THE HAMSTER PRODUCED BY RESERPINE
- 1 November 1958
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 29 (3) , 369-374
- https://doi.org/10.1530/acta.0.0290369
Abstract
Following the administration of reserpine, 0.5 mg/kg, a complete depletion of yellow-brown pigment was found in the adrenal medulla of hamster tissue sections after oxidation with potassium iodate (Hillarp-Hofelt''s reagent, specific for norepinephrine). After oxidation with chrome salts, however, the cell groups located at the periphery of the medulla show no chromaffin, and only the central portion of the gland rich in epinephrine exhibits a chromaffin-positive reaction. These results suggest that in the dosage used, reserpine causes an almost selective depletion of norepinephrine in the adrenal medulla of the hamster.Keywords
This publication has 4 references indexed in Scilit:
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- DISTRIBUTION OF FLUORESCING ISLETS, ADRENALINE AND NORADRENALINE IN THE ADRENAL MEDULLA OF THE HAMSTERActa Endocrinologica, 1955
- HISTOCHEMICAL DEMONSTRATION OF NORADRENALINE AND ADRENALINE IN THE ADRENAL MEDULLAJournal of Histochemistry & Cytochemistry, 1955
- SELECTIVE DEPLETION OF THE ADRENALINE CONTENT OF THE SUPRARENAL GLAND BY THE INJECTION OF INSULIN IN THE CAT1Endocrinology, 1953