Preventing Cancer by Disrupting Progression of Precancerous Lesions

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Abstract
In this issue of the Journal, Correa et al. (1) provide results from the first reported randomized intervention trial of the effects of anti-Helicobacter pylori treatment and of vitamin supplementation on precancerous lesions of the stomach. The findings are encouraging, with evidence that therapy for H. pylori and supplementation with β-carotene or vitamin C may help limit progression and enhance regression of conditions believed to be in the pathway of gastric cancer.