A NEW RAT MUTANT WITH DEFECTIVE OVERHAIRS AND SPONGY DEGENERATION OF THE CENTRAL NERVOUS-SYSTEM - CLINICAL AND PATHOLOGIC-STUDIES
- 1 January 1982
- journal article
- research article
- Vol. 32 (1) , 70-73
Abstract
A new spontaneous autosomal recessive mutation with a nervous disorder and a hair anomaly occurred in a colony of Sprague Dawley rats. The animals developed a generalized body tremor at about 15 days of age, and with increasing age a progressive flaccid paresis occurred. Light microscopy revealed spongy changes in the CNS. The mutant was designated zitter rat (zi).This publication has 4 references indexed in Scilit:
- CHRONIC WASTING DISEASE OF CAPTIVE MULE DEER: A SPONGIFORM ENCEPHALOPATHYJournal of Wildlife Diseases, 1980
- MYELIN DEFICIENCY (MD) - NEUROLOGIC MUTANT IN THE WISTAR RAT1979
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- Spongy degeneration of the central nervous system in kittensActa Neuropathologica, 1976