Stereoselective Formal Synthesis of Pseudodistomin C
- 20 December 2001
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (2) , 185-187
- https://doi.org/10.1021/ol010221p
Abstract
[reaction: see text] Trisubstituted benzenesulfonylmethylpiperidine 4, in which the substituents are all cis to each other, is a direct synthetic precursor of the cytotoxic marine alkaloid pseudodistomin C; it has been synthesized with total diastereoselectivities from (S)-pyroglutaminol.Keywords
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