Substrate Specificity of Fucosyltransferase Purified from Human Parotid Saliva
- 1 March 1987
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 66 (3) , 756-760
- https://doi.org/10.1177/00220345870660031001
Abstract
The purified fucosyltransferase from human parotid saliva was shown to transfer fucose from GDP-fucose onto the oligosaccharide chains containing the Galβl→3GlcNAc or Gal β 1→4GlcNAc/Glc sequences. Competition studies between asialotransferrin and either lacto-N-fucopentaose 1 or 2'-fucosyllactose provided evidence that both the substrates competed for a common enzyme active site. These results suggest that the fucosyltransferase activities for the three acceptors may be catalyzed by the same enzyme.This publication has 22 references indexed in Scilit:
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