Crystal structures of the SH2 domain of grb2: highlight on the binding of a new high-affinity inhibitor
- 1 February 2002
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 315 (5) , 1167-1177
- https://doi.org/10.1006/jmbi.2001.5299
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- SH2/SH3 signaling proteinsPublished by Elsevier ,2004
- SH2 and SH3 domains as targets for anti-proliferative agentsPublished by Elsevier ,2001
- Up-regulation of the protein tyrosine phosphatase SHP-1 in human breast cancer and correlation withGRB2 expressionInternational Journal of Cancer, 2000
- Inhibitors of RAS signal transduction as antitumor agentsBiochemical Pharmacology, 2000
- Overexpression of Grb2 in Inflammatory Lesions and Preneoplastic Foci and Tumors Induced by N-Nitrosodimethylamine in Helicobacter hepaticus—Infected and -Noninfected A/J MiceToxicologic Pathology, 2000
- Progress in the Development of Inhibitors of SH2 DomainsCurrent Pharmaceutical Design, 2000
- Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptideJournal of Molecular Biology, 1999
- MODULAR PEPTIDE RECOGNITION DOMAINS IN EUKARYOTIC SIGNALINGAnnual Review of Biophysics, 1997
- Structural basis for specificity of GRB2-SH2 revealed by a novel ligand binding modeNature Structural & Molecular Biology, 1996
- SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling ProteinsScience, 1991