THE EFFECT OF VARIOUS DOSES OF OESTRADIOL 17- ON GLYCOGEN DEPOSITION IN THE RAT UTERUS, CERVIX AND VAGINA

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Abstract
Administration of estradiol benzoate, 5 to 200 [mu]g, intramuscularly daily for 3 days, results in glycogen deposition in the uterus and cervix of castrated Wistar rats. The relation between dose of estrogen and amount of glycogen deposited is not, however, linear nor did all portions of the tract respond in a similar manner. The glycogen level of the vagina was not affected by the hormone administration, while progesterone lowered the glycogen content of all portions of the tract. The glycogen metabolism of the mammalian female genital tract is briefly reviewed and discussed.