Paracentric inversions in man

Abstract
Two new cases of familial paracentric inversions, 46,Xy,inv(3)(p21.1p25) and 46,XY,inv(7) (q22.3q6.1) are presented. A review of published cases suggests that prenatal diagnosis for carriers of paracentric inversions is not warranted. Care must be exercised in eliminating the possibility of insertions.