HEMOGLOBIN STUDIES ON THE BLOOD OF FEMALE MICE OF THE CBA STRAIN: EFFECTS OF AGE, DIET, STRAIN, AND REPRODUCTION

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Abstract
829 Hb detns. on the tail blood of CBA mice were made by the acid hematin method, values being read colorimetrically against a calibrated Hb disk. Blood was secured at 40 day intervals from 40 to 480 days of age for virgins, and from 120 to 920 days for breeders. Maximum averages of 16.9 gms. per 100 cc. of blood were obtained from 26 virgins 80 days old; 17.4 gms. from a small group of 4 virgins 120 days old; and 16.3 gms. from 37 breeders 200 days old. Avg. values for breeders describe 2 relatively level plateaus which average 15.9 gms. for the 1st period of 160 days and 14.2 gms. for the 2d interval of 240 days. The plateaus are separated by an interval of 120 days during which the hemoglobin was lowered 1.2 gms. A higher level of Hb was observed in mice fed fox chow than in those fed an oatmeal mixture. Age, diet, and strain should be taken into account in interpreting data dealing with concs. of Hb in the blood of mice.

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