Histometrical Investigations of Arteries in Reference to Arterial Hypertension

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Abstract
A histometrical method is described which is applied to the perfectly stretched internal elastic membrane. Determinations of arterial radius and medial thickness enabled the formulation of a general equation for the relationship between these 2 (which had been found to be constant). Studies were made of renal and superior mesenteric arteries in non-hypertensive cases divided into age groups. Medial index (ratio of arterial radius to medial thickness) was independent of age and permitted establishment of normal limits. In hypertensives, medial hypertrophy occurs in both arteries and is unequally distributed according to the dimensions of the branchs; this may lead to the observed functional differences as regulatory activity is transferred from smaller to larger branches.

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