Actinomycin D decreases protein kinase C content and induces neuritogenesis in neuroblastoma cells
- 25 March 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 280 (2) , 245-246
- https://doi.org/10.1016/0014-5793(91)80302-j
Abstract
We have previously reported that inhibition of protein kinase C induces differentiation of neuroblastoma cells in culture. It is shown now that actinomycin D, a well known inhibitor of DNA synthesis, reduces selectively the content of protein kinase C and induces neuritogenesis in Neuro 2a cells in culture.Keywords
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