An Improved Method for the Purification of Hepatic Proliferation Inhibitor by Anion-Exchange HPLC
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 5 (4) , 751-756
- https://doi.org/10.1080/01483918208060583
Abstract
An improved method for the purification of hepatic proliferation inhibitor from rat liver by means of anion-exchange HPLC has been developed. The inhibitor can be purified on an anion exchange HPLC column by using a linear sodium phosphate gradient. The HPLC method allows repeated use of one column and is both rapid and reproducible. The hepatic proliferation inhibitor isolated by this method retains all of its biological activity and is homogeneous as revealed by reverse-phase HPLC.This publication has 4 references indexed in Scilit:
- SPECIFIC-INHIBITION OF PROLIFERATION OF NONMALIGNANT RAT HEPATIC CELLS BY A FACTOR FROM RAT-LIVER1980
- Control of Liver Growth by Growth Inhibitors (Chalones)Published by Springer Nature ,1979
- Chalones Specific endogenous mitotic inhibitorsFEBS Letters, 1973