OCULAR AND ORAL PEMPHIGUS

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Abstract
Ocular pemphigus occurs about once in 46,000 cases of ocular disease. The cause is unknown, the prognosis unfavorable and the treatment of no appreciable benefit. Defined briefly, pemphigus is a systemic disease characterized by successive crops of bullae which may involve the skin, mucous membrane of the respiratory and gastro-intestinal tracts, conjunctivae and viscera. There seems to be a certain connection with atrophic nerve changes. It has been noticed in debilitated persons whose resistance was impaired, but there is no definite proof that debility is the sole cause. The lesions on the mucosa of the mouth may form small vesicles, but many rupture within from fifteen minutes to one hour after their formation. Some lesions may heal and others form on the mucosa, making it appear as a ragged, grayish-white, macerated membrane; there may also be numerous elevated granulations. In Vincent's angina there is a characteristic punched-out area with

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