The block of thyroglobulin synthesis, which occurs upon transformation of rat thyroid epithelial cells, is at the transcriptional level and it is associated with methylation of the 5′ flanking region of the gene

This publication has 22 references indexed in Scilit:

• Detection of specific sequences among DNA fragments separated by gel electrophoresis
  Published by Elsevier ,2006
• One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes.
  Molecular and Cellular Biology, 1987
• CpG-rich islands and the function of DNA methylation
  Nature, 1986
• A mos oncogene-containing retrovirus, myeloproliferative sarcoma virus, transforms rat thyroid epithelial cells and irreversibly blocks their differentiation pattern
  Journal of Virology, 1985
• Structural organization of the 3′ half of the rat thyroglobulin gene
  Nucleic Acids Research, 1984
• Dissociation between transformed and differentiated phenotype in rat thyroid epithelial cells after transformation with a temperature-sensitive mutant of the Kirsten murine sarcoma virus.
  Molecular and Cellular Biology, 1983
• DNA METHYLATION AND GENE ACTIVITY
  Annual Review of Biochemistry, 1983
• Loss of type I procollagen gene expression in SV40-transformed human fibroblasts is accompanied by hypermethylation of these genes
  Nucleic Acids Research, 1982
• DNA Methylation--A Regulatory Signal in Eukaryotic Gene Expression
  Journal of General Virology, 1981
• Modification of the methylation pattern in the vicinity of the chicken globin genes in avian erythroblastosis virus transformed cells
  Nucleic Acids Research, 1981