Isolation of Viruses from Mosquitoes Collected at Lumbo, Mozambique
- 1 September 1962
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 11 (5) , 678-682
- https://doi.org/10.4269/ajtmh.1962.11.678
Abstract
Summary Twelve strains of a hitherto unknown virus have been isolated from Aedes (Skusea) pembaensis collected in 1959 and 1960 at Lumbo in northeastern Mozambique. The name proposed for the agent is Lumbo. Lumbo virus is filterable and withstands lyophilization but is sensitive to sodium desoxycholate. It is pathogenic for adult mice and hamsters by the intracerebral but not the intraperitoneal inoculation route. Vervet monkey, yellow baboon, bushbaby and guinea pig develop an immune response to the virus without showing signs of illness. Viremia was detected on the 3rd and 4th postinoculation days in a vervet monkey. Of 128 human sera collected at Lumbo and Ndumu, northern Natal, in the tropical corridor in southeastern Africa, 16 contained neutralizing antibodies; all of 175 human sera collected in Angola and the Caprivi Strip were negative.Keywords
This publication has 4 references indexed in Scilit:
- The California Complex of Arthropod-Borne Viruses and Its Relationship to the Bunyamwera Group Through Guaroa VirusThe American Journal of Tropical Medicine and Hygiene, 1962
- Isolation of Viruses from Mosquitoes Collected at Lumbo, MozambiqueThe American Journal of Tropical Medicine and Hygiene, 1962
- Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne VirusesThe American Journal of Tropical Medicine and Hygiene, 1958
- Action of Sodium Desoxycholate on Arthropod-Borne VirusesExperimental Biology and Medicine, 1957