Total synthesis of (±)-prostaglandin I₂methyl ester and (±)-15-epi-prostaglandin I₂methyl ester

1 January 1981

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 17,p. 922-924
https://doi.org/10.1039/c39810000922

Abstract

Prostacyclin (prostaglandin I₂) methyl ester has been prepared; the key step was an aldol reaction between a cyclopentanone enolate and the cyclopentenyl-acetaldehyde derivative (4).

Keywords

TOTAL SYNTHESIS

Total synthesis of (±)-prostaglandin I2methyl ester and (±)-15-epi-prostaglandin I2methyl ester

Abstract

Keywords

Total synthesis of (±)-prostaglandin I₂methyl ester and (±)-15-epi-prostaglandin I₂methyl ester