Calcium-Binding Proteins of the EF-Type
- 1 January 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Cardiovascular Pharmacology
- Vol. 12, 30-37
- https://doi.org/10.1097/00005344-198806125-00006
Abstract
Calcium, acting as second messenger, are through-target proteins that contain an EF-hand structure. Based on this general principle, EF-hand structures can be predicted from the amino acid sequence of a protein. Most recently, several new members of the Ca2+-binding protein family have been discovered, e.g., the cystic fibrosis antigen (CFAg), the macrophage migration inhibitory factor related proteins (MRP-8 and −14), non-muscle α-actinin, and uvomorulin, the latter belonging to the group of cell adhesion molecules. Additionally, new information about the physiological functions of S-100 proteins, calbindins, calretinin as well as parvalbumin were observed and some of the these results are discussed.Keywords
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