TONSILLECTOMY IN EXPERIMENTAL POLIOMYELITIS1

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Abstract
Although cynomolgus monkeys may sometimes become infected following the ingestion of poliomyelitis virus (rodent-adapted Y-SK strain), their susceptibility has been shown to be greatly increased in this series of expts. if they are tonsillectomized immediately prior to the exposure to virus. This has not been found to be true for rhesus of African green monkeys. Two of 3 cynomolgus monkeys which developed exptl. poliomyelitis were found to excrete virus with their stools the day before paralysis. Five nonparalyzed monkeys did not excrete virus in the 4-weeks observation period. Of 14 tonsillectomized monkeys which subsequently developed poliomyelitis, only 2 could be said to show the bulbar form of the disease. In addition 2 monkeys exhibited facial paralysis together with paralysis of the limbs on the first day of illness. Paralysis of one or more extremities was the first sign of disease in the reamaining 10.