Solubility and Related Physicochemical Properties of Narcotic Analgesics
Open Access
- 1 January 1988
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 05 (9) , 580-586
- https://doi.org/10.1023/a:1015994030251
Abstract
The physicochemical properties of select opioid and anilinopiperidine narcotic analgesics were investigated. The solubilities of the narcotics in hexane and water and, for morphine, in other organic...This publication has 12 references indexed in Scilit:
- Penetration of guinea pig skin by acyclovir in different vehicles and correlation with the efficacy of topical therapy of experimental cutaneous herpes simplex virus infectionAntimicrobial Agents and Chemotherapy, 1984
- Solubility of Hydrocortisone in Organic and Aqueous Media: Evidence for Regular Solution Behavior in Apolar SolventsJournal of Pharmaceutical Sciences, 1983
- BIOTRANSFORMATION OF FENTANYL .3. INFLUENCE OF CHRONIC DRUG ADMINISTRATION UPON DISTRIBUTION, METABOLISM AND EXCRETION IN THE RAT1983
- BIOTRANSFORMATION OF FENTANYL .2. ACUTE DRUG-INTERACTIONS IN RATS AND MEN1982
- Improving Analgesic TherapyAnesthesiology, 1980
- Pharmacokinetics of fentanyl as determined by radioimmunoassayClinical Pharmacology & Therapeutics, 1978
- Morphine metabolism in manClinical Pharmacology & Therapeutics, 1974
- Correlation and Prediction of Mass Transport across Membranes I: Influence of Alkyl Chain Length on Flux-Determining Properties of Barrier and DiffusantJournal of Pharmaceutical Sciences, 1972
- Calculation of Partial Molal Volume in Micellar SystemsJournal of Pharmaceutical Sciences, 1972
- Significance of Vehicle Composition I: Relationship between Topical Vehicle Composition, Skin Penetrability, and Clinical EfficacyJournal of Pharmaceutical Sciences, 1971