The effect of contrast media on the aortic endothelium of rats.
- 1 June 1983
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 147 (3) , 685-688
- https://doi.org/10.1148/radiology.147.3.6844605
Abstract
The effect of diatrizoate, ioxitalamate, metrizamide and ioxaglate on the aortic endothelium of the rat was investigated using transmission electron microscopy and DNA synthesis autoradiography. One ml of each contrast medium, containing 300 mg I/ml, was injected into the aorta. The types of lesions seen on EM and the rate of DNA synthesis seen on autoradiography established the degree of endothelial damage produced. Of the 4 contrast agents tested, ioxaglate produced the least amount of cellular change.This publication has 1 reference indexed in Scilit:
- Endothelial cells and “cement” linesThe Journal of Pathology and Bacteriology, 1959