Synthesis of a model bicyclic C-O-D-O-E ring of vancomycin by a one-pot, double SNAr based macrocyclization
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 9,p. 1029-1030
- https://doi.org/10.1039/cc9960001029
Abstract
Double cyclization of linear pentapeptide 3 by treatment with CsF in DMF at –5 °C gives a model bicyclic CODOE ring 2 of vancomycin in a one-pot fashion.Keywords
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