SOME PHARMACOLOGICAL PROPERTIES OF MUREXINE (UROCANOYLCHOLINE)
Open Access
- 1 March 1958
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology and Chemotherapy
- Vol. 13 (1) , 103-106
- https://doi.org/10.1111/j.1476-5381.1958.tb00200.x
Abstract
Murexine (urocanoylcholine, [2–β-imidazol-4(5)-ylacryloyloxyethyl] trimethylammonium bromide) has been shown to possess ganglion stimulating and neuromuscular blocking actions in cat, dog and rat. The blockade has been shown to be of the depolarizing type both on the basis of the resemblance of the pharmacological properties of the substance to that of known depolarizing blocking agents, and also directly by recording the depolarization produced in the endplate region of the gracilis muscle of the rat.Keywords
This publication has 9 references indexed in Scilit:
- Physiologically active choline esters in certain marine gastropods and other invertebratesThe Journal of Physiology, 1957
- THE MECHANISM OF ACTION OF MUREXINE ON NEUROMUSCULAR TRANSMISSION IN THE FROGBritish Journal of Pharmacology and Chemotherapy, 1957
- THE ENZYMATIC HYDROLYSIS OF IMIDAZOLEACRYLOYLCHOLINE (MUREXINE) AND IMIDAZOLEPROPIONYLCHOLINE (DIHYDROMUREXINE) BY VARIOUS CHOLINESTERASESBritish Journal of Pharmacology and Chemotherapy, 1957
- THE PHARMACOLOGICAL ACTIONS OF MUREXINE (UROCANYLCHOLINE)British Journal of Pharmacology and Chemotherapy, 1957
- Interrelationship of Murexine, Dihydromurexine and Human Cholinesterases.Experimental Biology and Medicine, 1957
- THE CHOLINERGIC ACTIVITY OF TETRAKIS-(DIMETHYLAMINO-METHYL)-METHANE TETRAMETHOBROMIDE1954
- *ISOLIERUNG DES MUREXINS AUS HYPOBRANCHIALDRUSENEXTRAKTEN VON MUREX TRUNCULUS UND SEINE IDENTIFIZIERUNG ALS BETA-[IMIDAZOLYL-4(5)]-ACRYLCHOLIN1953
- Depolarization of the motor end‐plate by decamethonium and acetylcholineThe Journal of Physiology, 1951
- Die fermentative Spaltung des AcetylcholinsPflügers Archiv - European Journal of Physiology, 1934