Acute Cardiovascular Consequences of Anterior Descending Coronary Artery Occlusion in Unanesthetized Monkey

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Abstract
The acute response of the unanesthetized [primates Macaca mulatta and Papio anubis] to occlusion of the anterior descending coronary artery consists of a pressor response, tachycardia and increase in d(LVP)/dt [change in left ventricular pressure with time]. This response resembles that reported for comparable situations in man, and may be due to elevated cardiac sympathetic tone. The non-human primates provide attractive models for experimental study of anterior MI [myocardial infarction].