WORK OF BREATHING, INTRA‐THORACIC PRESSURE AND CLINICAL FINDINGS IN A GROUP OF BABIES WITH BRONCHIOLITIS

Abstract
Total work of breathing was measured on 55 occasions on 26 [human] babies with acute bronchiolitis using a respiratory jacket to measure tidal volume and a nasogastric tube to record esophageal pressure. Work of breathing was increased 6-fold on average and on 1 occasion exceeded 40 times the expected. Approximately 40% of the intrathoracic pressure swing was positive relative to atmospheric. It was not possible to correlate the work of breathing measurements with detailed clinical assessments.