Effect of Oral Omeprazole on Fasting and Meal Stimulated Serum Gastrin and Serum Pepsinogen I Levels in Healthy Volunteers
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 21 (sup118) , 160-161
- https://doi.org/10.3109/00365528609090928
Abstract
Omeprazole is a potent, long acting inhibitor of gastric acid secretion. It acts by blocking the H+K+ATPase in the parietal cell. Intragastric neutralization causes a rise in serum gastrin levels and, after longer periods of time, hyperfunction of gastrin producing cells may result. Therefore, the effects and after-effects of oral omeprazole on fasting and meal stimulated serum gastrin and serum pepsinogen I levels were studied.Keywords
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