Identification of the b, d, and e analogs of vitamin B12 as monocarboxylic acids by 15N NMR spectroscopy
- 1 February 1989
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Chemistry
- Vol. 27 (2) , 127-129
- https://doi.org/10.1002/mrc.1260270206
Abstract
15N NMR spectra of b−, d−, and e‐cyanocobalamin (vitamin B12) and the products of their amidation with 15N‐labeled ammonia show that these analogs are monocarboxylic acids of vitamin B12 which result from hydrolysis at the respective propionamide groups.Keywords
This publication has 14 references indexed in Scilit:
- Is it isomerization of cobalamins or simple hydrolysis of a propionamide side chain?Inorganica Chimica Acta, 1987
- The principal components of synthetic vitamin B'12Inorganic Chemistry, 1986
- Significance of isomerization in hydroxocobalaminBiochemical and Biophysical Research Communications, 1984
- 1H NMR Studies of the isomers of dicyanocobalamin and dicyanocobinamidePolyhedron, 1982
- The interaction of cyanocobalamin and some of its analogs with manganese(II) and gadolinium(III)Archives of Biochemistry and Biophysics, 1982
- Carbon-13 nuclear magnetic resonance studies of cyanocobalamin and several of its analogsBiochemistry, 1982
- 31P nuclear relaxation studies of para- and diamagnetic cobalamins in their two isomeric formsBiochimica et Biophysica Acta (BBA) - Protein Structure, 1981
- Carbon-13 nuclear magnetic resonance studies of the monocarboxylic acids of cyanocobalamin. Assignments of the b-, d-, and e-monocarboxylic acidsJournal of the American Chemical Society, 1980
- Role of peripheral side chains of vitamin B12 coenzymes in the reaction catalyzed by dioldehydraseBiochemistry, 1979
- Applications of natural-abundance nitrogen-15 nuclear magnetic resonance to large biochemically important molecules.Proceedings of the National Academy of Sciences, 1975