Liver function tests after hypoglycaemia in insulin‐dependent‐diabetic patients

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Abstract
Liver function tests were measure in 16 patients with insulin‐dependent diabetes mellitus following controlled insulin‐induced hypoglycaemia (Group A) and in 12 patients admitted to an Accident And Emergency Department in hypoglycaemic coma (Group B). Bilirubin, alanine aminotransferase and aspartate aminotransferase were normal in all patients. Gamma‐glutamyl transferase was elevated in three patients in Group B, of whom two were receiving phenytoin therapy and the third had a history of excessive alcohol consumption. It appears that significant abnormalities of liver function tests are not a common sequel of hypoglycaemia in diabetic patients in the absence of predisposing liver disease.