A Convenient Synthesis of 2-Arylmethylindoles
- 1 January 1992
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1992 (09) , 835-836
- https://doi.org/10.1055/s-1992-26239
Abstract
Methoxy substituted arenes 2 were alkylated with 1-benzenesulfonyl-2-bromomethyl-3-phenylthioindole (1) using palladium chloride to give the alkyl substituted arenes 3, which on Raney nickel followed by sodium hydroxide treatment gave 2-arylmethylindoles 4 in good yield.Keywords
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