INTERFERON INDUCTION IN BOVINE AND FELINE MONOLAYER-CULTURES BY 4 BLUETONGUE VIRUS SEROTYPES

  • 1 January 1982
    • journal article
    • research article
    • Vol. 46  (1) , 100-102
Abstract
The interferon inducing ability of the bluetongue viruses was studied in bovine and feline monolayer cultures inoculated with each of 4 bluetongue virus serotypes. Interferon was assayed by a plaque reduction method in monolayer cultures with vesicular stomatitis virus as challenge virus. Interferon was produced by bovine turbinate, Georgia bovine kidney and Crandell feline kidney monolayer cultures in response to bluetongue virus serotypes 10, 11, 13 and 17. The antiviral substances produced by the bluetongue virus infected cultures had properties of interferon.