Chemical and Photochemical Ligation of Oligonucleotide Blocks
- 1 May 1997
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 16 (5-6) , 643-652
- https://doi.org/10.1080/07328319708002929
Abstract
Several efficient means for joining oligonucleotides in dilute solution by non-natural internucleotide bridges are discussed. It is also shown that an oligonucleotide containing a -OP(O)(O−)S- link can hnction as an effective template in PCR amplification and that oligonucleotide probes containing stilbenedicarboxamide groups can serve in monitoring the presence of mismatched bases in an oligonucleotide target.Keywords
This publication has 20 references indexed in Scilit:
- Sequence-Dependent Structural Variations of DNA Revealed by Chemical LigationNucleosides and Nucleotides, 1994
- Oligonucleotide circularization by template-directed chemical ligationNucleic Acids Research, 1993
- Template-directed synthesis: use of a reversible reactionJournal of the American Chemical Society, 1992
- Nonenzymatic ligation of double-helical DNA by alternate-strand triple helix formationNucleic Acids Research, 1992
- Synthesis of a conformationally restricted DNA hairpinThe Journal of Organic Chemistry, 1991
- Disulfide-crosslinked oligonucleotidesJournal of the American Chemical Society, 1991
- Chemical development in the design of oligonucleotide probes for binding to DNA and RNABiochimie, 1988
- Autocatalytic synthesis of a tetranucleotide analogueNature, 1987
- Template-directed polymerization of oligoadenylates using cyanogen bromideBiochemistry, 1986
- Studies on Some Interactions and Reactions of Oligonucleotides in Aqueous Solution*Biochemistry, 1966