A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).
Open Access
- 1 February 1994
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 269 (7) , 5241-5248
- https://doi.org/10.1016/s0021-9258(17)37680-9
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- Signal transduction in neutrophil activation Phosphatidylinositol 3‐kinase is stimulated without tyrosine phosphorylationFEBS Letters, 1992
- The inhibition of phosphatidylinositol 3-kinase by quercetin and analogsBiochemical and Biophysical Research Communications, 1992
- Vascular Signal Transduction and AtherosclerosisAnnals of the New York Academy of Sciences, 1990
- Platelet‐derived growth factor regulates actin isoform expression and growth factor regulates actin isoform expression and growth state in cultured rat aortic smooth muscle cellsJournal of Cellular Physiology, 1990
- The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinaseNature, 1989
- An inositol tetrakisphosphate-containing phospholipid in activated neutrophilsNature, 1988
- Inhibition of phosphorylase kinase, and tyrosine protein kinase activities by quercetinBiochemical and Biophysical Research Communications, 1985
- Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: Inhibition by quercetinBiochemical and Biophysical Research Communications, 1984
- Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetinBiochemical and Biophysical Research Communications, 1983
- Synthesis of 2‐aminochromones. Studies on the nucleophilic displacement of sulphinyl and sulphonyl groups in the 2‐position of 5,8‐dimethoxychromoneJournal of Heterocyclic Chemistry, 1981