7,8‐Dioxochlorpromazine, synthesis and properties
- 1 April 1975
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 12 (2) , 239-242
- https://doi.org/10.1002/jhet.5570120205
Abstract
7,8‐Dihydroxychlorpromazine and 2‐chloro‐7,8‐dihydroxyphenothiazine were converted to the corresponding 7,8‐dioxo compounds by oxidation with tetrachloro‐o‐quinone. Spectral properties indicate that the 7,8‐dioxo compounds exist in zwitterionic forms reminiscent of aminochromes. The 7,8‐dioxochlorpromazine is proposed as a possible metabolite of chlorpromazine.Keywords
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