Interaction of pepstatin with pig pepsinogen
- 1 August 1976
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 157 (2) , 499-502
- https://doi.org/10.1042/bj1570499
Abstract
In contrast with pepsin, pepsinogen does not bind pepstatin at pH values between 5.3 and 2.5. Pepsinogen is not retarded by pepstatin immobilized on to aminohexyl-Sepharose at pH5.3 or 4.1, whereas at pH3.0 activation takes place during the chromatography, with retardation of the resultant pepsin.This publication has 14 references indexed in Scilit:
- Interaction of human cathepsin D with the inhibitor pepstatinBiochemical Journal, 1976
- Conversion of pepsinogen into pepsin is not a one-step processBiochemical Journal, 1976
- An assay to differentiate the “true” activity of pepsin from the potential activity of pepsinogenAnalytical Biochemistry, 1975
- Conversion of pepsinogen to pepsin. Further evidence for intramolecular and pepsin-catalyzed activation.Journal of Biological Chemistry, 1975
- The activation of bovine pepsinogen. Sequence of the peptides released, identification of a pepsin inhibitor.1974
- Affinity chromatographic differentiation of lactate dehydrogenase isoenzymes on the basis of differential abortive complex formationFEBS Letters, 1974
- MECHANISM OF INHIBITION OF PEPSIN BY PEPSTATIN. IIThe Journal of Antibiotics, 1974
- A Spectrophotometric Investigation of the Pepsinogen-Pepsin ConversionJournal of Biological Chemistry, 1972
- Kinetics and Mechanism of Pepsinogen ActivationJournal of Biological Chemistry, 1972
- EFFECT OF PEPSTATIN ON ACID PROTEASESThe Journal of Antibiotics, 1971