PROTECTIVE EFFECT OF DISODIUM-CROMOGLYCATE ON ALLERGEN-INDUCED BRONCHOCONSTRICTION AND INCREASED HYPERRESPONSIVENESS - A DOUBLE-BLIND PLACEBO-CONTROLLED STUDY

  • 1 October 1986
    • journal article
    • research article
    • Vol. 57  (4) , 295-300
Abstract
The protective effect of 40 mg cromolyn on allergen-induced late response and increased hyperresponsiveness were studied in five asthmatic children to whom this drug and saline placebo were administered 20 minutes before allergen inhalation, at random, double-blind. Cromolyn reduced the magnitude of early and late responses and abolished the increase in methacholine responsiveness.