Rare occurrence of IgVH gene translocations and restricted IgVH gene repertoire in ocular MALT-type lymphoma
- 1 February 2008
- journal article
- Published by Ferrata Storti Foundation (Haematologica) in Haematologica
- Vol. 93 (2) , 319-321
- https://doi.org/10.3324/haematol.11950
Abstract
FISH studies on 37 ocular MALT-type lymphomas yielded chromosomal translocations affecting MAL andT1 BCL10 in 1 case each, no evidence for a break in the FOXP1 locus, and trisomy 3 in 14 out of 34 cases (41%). Three out of 8 cases analyzed used the highly mutated VH3-23 gene and showed ongoing somatic hypermutations.Keywords
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