Terminal deoxynucleotidyl transferase as a hematopoietic cell marker
Open Access
- 1 December 1979
- journal article
- Published by American Society of Hematology in Blood
- Vol. 54 (6) , 1203-1215
- https://doi.org/10.1182/blood.v54.6.1203.1203
Abstract
Terminal deoxynucleotidyl transferase (TdT) is an intracellular protein characteristic of certain primitive lymphocytes in normal thymus and bone marrow. It can be detected by enzyme assay or immunocytochemical staining. High levels of enzyme and increased numbers of TdT+ cells are found in some lymphoblastic leukemias and lymphomas. Analysis for TdT thus provides a useful adjunct in the differential diagnosis of leukemia.Keywords
This publication has 0 references indexed in Scilit: