• 1 January 1981
    • journal article
    • research article
    • Vol. 19  (3) , 197-201
Abstract
The nucleation kinetics of calcium oxalate were studied in the presence and absence of sodium urate monohydrate crystalline material by 3 experimental measurements. These included analytical determinations of Ca and radiotracer analysis of oxalate in the metastable calcium oxalate solution phase and the independent detection of new crystal nuclei by solution turbidity measurements. None of the methods evidenced that sodium urate increases the induction time for nucleation of calcium oxalate, in contrast to previously published reports. These results are discussed in relation to the mechanisms advanced to explain the interdependency of hyperuricosuria and calcium oxalate urolithiasis.