THE SIGNIFICANCE OF GASTRIC ULCER WITH RESPECT TO GASTRIC CANCER

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Abstract
During the past decade there has been a growing conviction among clinical and laboratory workers that there exists an increasing number of cases clinically admitting a diagnosis only of chronic gastric ulcer which do not pursue an orthodox course of chronicity, but often rapidly assume aspects of malignant disease. If such cases come to laparotomy or necropsy, the surgeon or pathologist demonstrates cancer. Conversely, surgically and pathologically proved cases of gastric cancer frequently reveal an early clinical history, which at any stage prior to the terminal period of evident malignancy might logically be interpreted clinically as chronic gastric ulcer. The subject has etiologic, diagnostic and prognostic aspects. Inasmuch as this group of cases satisfies the diagnostic requirements for gastric ulcer and this process of whatever nature it may be later assumes characteristics that we associate with malignancy, and as we have no known medical cure for gastric neoplasms, it would

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