CELL MARKER ANALYSIS IN ACUTE MONOCYTIC LEUKEMIAS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 49  (6) , 895-901
Abstract
Leukemic cells from 9 cases of acute monocytic leukemia (AMoL) were characterized by multiple differentiation markers. Cells in most cases were phagocytic, carried an Fc receptor and stained positively for .alpha.-naphthyl acetate esterase but negatively for naphthol AS-D chloroacetate esterase. Subtle differences in marker expression were observed which suggested different degrees of leukemic cellular maturation or activation. Cell marker analysis proved to be a useful adjunct to conventional morphology in confirming the diagnosis and recognition of neoplastic cells in AMoL, and may provide insight into the functional state of these cells.

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