Tuberculous Psoas Muscle Abscess Following Chemopeophylaxis with Isoniazid in a Patient with Human Immunodeficiency Virus Infection

Abstract
A 34-year-old man with human immunodeficiency virus infection and disseminated Mycobacterium aviumand Mycobacterium intrace/lulare infection developed a right psoas muscle abscess due to Mycobacterium tuberculosis. The abscess occurred 18months after completion of a 12-month course of chemoprophylaxis with isoniazid that was given because of a positive reaction with purified protein derivative of tuberculin. The adjacent vertebrae did not appear to be involved. The abscess was drained with a percutaneously inserted catheter, and he received standard antituberculous chemotherapy. Three weeks into therapy, a second drainage with a catheter wasrequired. The isolation of two mycobacteria in this patient and the apparent failure of chemoprophylaxis with isoniazid are noted.

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