Chitosans for enhanced delivery of therapeutic peptides across intestinal epithelia: in vitro evaluation in Caco-2 cell monolayers
- 1 December 1997
- journal article
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 159 (2) , 243-253
- https://doi.org/10.1016/s0378-5173(97)00287-1
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- Absorption enhancing agents for the GI systemPublished by Elsevier ,2002
- Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitroJournal of Controlled Release, 1997
- Mucoadhesive polymers in peroral peptide drug delivery. V. Effect of poly(acrylates) on the enzymatic degradation of peptide drugs by intestinal brush border membrane vesiclesInternational Journal of Pharmaceutics, 1996
- Novel peroral dosage forms with protease inhibitory activities. II. Design of fast dissolving poly(acrylate) and controlled drug-releasing capsule formulations with trypsin inhibiting propertiesInternational Journal of Pharmaceutics, 1996
- Absorption-Enhancing Mechanism of EDTA, Caprate, and Decanoylcarnitine in Caco-2 CellsJournal of Pharmaceutical Sciences, 1996
- Mechanisms of absorption enhancement and tight junction regulationJournal of Controlled Release, 1994
- Cell-polarity dependent effect of chelation on the paracellular permeability of confluent caco-2 cell monolayersInternational Journal of Pharmaceutics, 1993
- Applications and Properties of ChitosanJournal of Bioactive and Compatible Polymers, 1992
- Loosening tight junctions. Lessons from the intestine.Journal of Clinical Investigation, 1989
- Occluding Junctions in MDCK Cells: Modulation of Transepithelial Permeability by the CytoskeletonJournal of Cellular Biochemistry, 1982