Fungal Transformation of (1R,2S,5R)-(−)-Menthol by Cephalosporium aphidicola
- 19 September 1998
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 61 (11) , 1340-1342
- https://doi.org/10.1021/np980057n
Abstract
Incubation of (1R,2S,5R)-(−)-menthol (1) with Cephalosporium aphidicola for 12 days yielded the six oxidized metabolites: 10-acetoxymenthol (2), 7-hydroxymenthol (3), 4α-hydroxymenthol (4), 3α-hydroxymenthol (5), 9-hydroxymenthol (6), and 10-hydroxymenthol (7). The structures of the novel compounds 2, 4, 5, and 7 were assigned by interpretation of their spectral data.Keywords
This publication has 5 references indexed in Scilit:
- The microbiological hydroxylation of some pinane monoterpenoids by Cephalosporium aphidicolaPhytochemistry, 1995
- The biotransformation of 8-epicedrol and some relatives by Cephalosporium aphidicolaPhytochemistry, 1995
- The incubation of 3α,16β-dihydroxyaphidicolane with Cephalosporium aphidicolaPhytochemistry, 1995
- The hydroxylation of globulol and 7-epiglobulol by Cephalosporium aphidicolaPhytochemistry, 1994
- An oxygen-18 study of the biosynthesis of the diterpenoid, aphidicolin in cephalosporium aphidicolaPhytochemistry, 1988