Synthesis at the molecular frontier
Top Cited Papers
- 8 July 2009
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 460 (7252) , 197-201
- https://doi.org/10.1038/460197a
Abstract
Driven by remarkable advances in the understanding of structure and reaction mechanisms, organic synthesis will be increasingly directed to producing bioinspired and newly designed molecules.Keywords
This publication has 45 references indexed in Scilit:
- Redesigning the Architecture of the Base Pair: Toward Biochemical and Biological Function of New Genetic SetsChemistry & Biology, 2009
- Biosynthesis of Aromatic Polyketides in BacteriaAccounts of Chemical Research, 2009
- Self-Consistent Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C via Controlled OligomerizationJournal of the American Chemical Society, 2008
- Variability in Content of the Anti-AIDS Drug Candidate Prostratin in Samoan Populations of Homalanthus nutansJournal of Natural Products, 2008
- Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) Repeat RNA−MBNL1 Interaction In Vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1)Journal of the American Chemical Society, 2008
- Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transportersProceedings of the National Academy of Sciences, 2008
- Efficient Synthetic Access to a New Family of Highly Potent Bryostatin Analogues via a Prins-Driven Macrocyclization StrategyJournal of the American Chemical Society, 2008
- Epoxide-Opening Cascades Promoted by WaterScience, 2007
- Evidence for the Rapid Conversion of Stephacidin B into the Electrophilic Monomer Avrainvillamide in Cell CultureJournal of the American Chemical Society, 2007
- Natural Products as Sources of New Drugs over the Last 25 YearsJournal of Natural Products, 2007