Further Observations on the Differential Inhibition of Coliform Bacilli and Rough Variants of Intestinal Pathogens
- 1 January 1949
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 3 (1) , 74-79
- https://doi.org/10.1099/00221287-3-1-74
Abstract
Differential inhibition of Gram-negative bacilli of intestinal origin depends on aerobiosis and the nature of the surface on which they are grown as well as on a synergism between bile salts and electrolytes. Electron microscope studies suggest that bile salts increase the cell-wall permeability to electrolytes. The ease with which organisms can be inhibited seems to be directly related to their altered cell-wall permeability. The observations indicate that one factor in the physiol. difference between rough and smooth variants of a single culture is the greater permeability of the rough variant to electrolytes in the presence of bile salts.Keywords
This publication has 1 reference indexed in Scilit:
- Modified leifson media for the isolatin ofB. dysenteriæ and pathogenic members of the colon-typhoid groupThe Journal of Pathology and Bacteriology, 1942