Administration of Bacterial Lipopolysaccharide to Rats Induces Heme Oxygenase-1 and Formation of Antioxidant Bilirubin in the Intestinal Mucosa
- 1 January 2000
- journal article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 45 (12) , 2313-2319
- https://doi.org/10.1023/a:1005626622203
Abstract
Heme oxygenase (HO)-1, the rate-limiting enzyme in heme degradation, is induced by oxidative stress and its major end product, bilirubin, is a potent physiological antioxidant. We studied the...Keywords
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